Eliminate two Eternal Sentinels to reduce number of spells that can be used by the enemy party.

Lastly, you must kill the main enemy, The Great Guardian.

The status that he inflicts on you’ve got the option to be removed by, e.g.

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When you manage to defeat the enemy, he will (shortly after that) resurrect.

However, you have to kill him only one more time.

The fight on Arena of the One is connected to the main storyline.

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This battle is very easy.

There isn’t anything complicated here - you must defeat enemies and stop them from reaching their destination.

The companions are much weaker than your party - Alexandar is the only real threat here.

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His entire team consists of copies of your companions.

However, you should remember that those copies can have abilities that your characters don’t.

After that you must run and interact with the marked point.

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Then, you must reach the marked point that will allow you to leave this area.

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Divinity: Original Sin II - Definitive Edition