There, beneath the corpse of a scientist (?)

you will have the chance to find the Shrink Gun.

Soon enough the aliens will start dropping reinforcements onto the roof.

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It’s a good idea to place a few mines beneath the vents and luring the enemies there.

There you will find another Shrink Gun.

By using it, you’re free to also unlockHe’s Got a hologram!

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Enemies will keep on coming, so keep an eye on your ammunition and explosives.

Use steroids as last resort and finish off them off personally.

A beer can also be useful in dire moments.

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By the end, two Commanders will appear.

If you still have the Holo Duke, now would be a great moment to use it.

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Duke Nukem Forever